Category Archives: hematology

Bleeding Patients on Dabigatran aka Pradaxa

By Dr. Ling Zang, MD Please refer to Indication: stroke prevention in atrial fibrillation Mechanism of action: reversible, competitive, direct thrombin inhibitor (downstream from other anticoagulants) Pharmacokinetics: Half time: 13 hours in patients with normal renal function (Cr clearance > … Continue reading

Posted in 1Intermediate, hematology | Leave a comment

Sickle Cell Disease Update

By Kei Ko, MD Sickle cell disease update Please refer to EMRAP episode Sickle cell Different phenotypes of sickle cell – Hemolytic¬† and vaso-occlusive Hemolytic Less resting hemoglobins and increased hemolysis Increased pulmonary hypertension and sudden death Vaso-occlusive Typical ED … Continue reading

Posted in 1Beginner, EMRAP, hematology | Leave a comment